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The principal cytochrome P450 isoenzyme included appears being CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. Somewhere around eighty five% of the oral dose appears within the urine inside 24 hours of administration, most as the glucuronide conjugate, with tiny quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity infor